Yusef D. Khesuani

Cofounder. Managing partners of 3D Bioprinting Solutions.
phone: +7 (499) 769-50-18

In 2007, he graduated from the Fundamental Medicine Department of the M.V. Lomonosov Moscow State University with the major in general medicine.

From 2008-2010, he completed an Executive MBA course at the Higher School of Management at the National Research University Higher School of Economics.

From 2004-2007, he worked at the P.A. Herzen Moscow Oncology Research Institute, Department of Nonsurgical Treatment Efficiency Appraisal.

The following were the main directions of research performed by the group with the aim to develop methos of cell therapy and introduce them into clinical practice:

  • biology studies of multipotent mesenchymal stromal cells (MMSC) from human and animal marrow and adipose tissues;
  • development of a safe method for cultivating human MMSC;
  • pre-clinical medical and biological tests in vitro (acute cytotoxicity and matrix properties assessment) and in vivo (biocompatibility of osteoconductive/osteoinductive potencies, speed of bioresorption) of synthetic (calcium-phosphate ceramics, calcium-phosphate cements, mineral-polymeric composite materials) and natural (skeletons of Scleractinian corals of certain families and their aquaculture) innovative domestically produced biomaterials for healing bone defect, selection of best suitable osteoplastic materials for clinical testing and subsequent introduction into clinical practice;
  • development and perfection of methods for performing pre-clinical medico-biological tests of materials for implantation;
  • development of tissue-engineering constructs from most promising samples of biomaterials and cultures of autological MMSC from human and animal marrow and adipose tissues for achieving optimal regeneration of bone tissues;
  • development of a method for the formation and use of natural and synthetic osteoplastic biomaterials as antibacterial “depots” and growth factors.

Hesuani is a coauthor of over 10 research papers.

Selected publications:

  1. Mironov V, Hesuani Y, Pereira F, Parfenov V, Koudan E, Mitryashkin A, Replyanski N, Kasyanov V, Knyazeva A, Bulanova E, Design and implementation of novel multifunctional 3D bioprinter. 3D Printing and Additive Manufacturing. 2015-0040.R1
  2. Elizabeth V. Koudan, Frederico DAS Pereira, Vladislav A. Parfenov, Vladimir A. Kasyanov, Yousef D. Hesuani, Elena A. Bulanova, and Vladimir A. Mironov. Spreading of tissue spheroids fabricated from primary human fibroblasts on the surface of electrospun microfiber polyurethane matrix (SEM study). Morphology, No. 6, 2015
  3. Vladimir Mironov, Yousef D. Khesuani, Elena A. Bulanova, Elizaveta V. Koudan, Vladislav A. Parfenov, Anastasia D. Knyazeva, Alexander N. Mitryashkin, Nikita Replyanski, Vladimir A. Kasyanov, Frederico Pereira D.A.S. Patterning of tissue spheroids biofabricated from human fibroblasts on the surface of electrospun polyurethane matrix using 3D bioprinter. International Journal of Bioprinting, No. 1, 2016

From 2008, Hesuani has been into commercial activities in the industry of health care in partnership with LLC Independent Laboratory INVITRO. He is experienced in launching and managing medical center chains both in Moscow and various regions of the Russian Federation. In 2014, together with partners, Hesuani opened the first franchising office under the Invitro.Expert program.

Hesuani is the founder of a company specializing in genetic research data interpretation.